⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313069 | 0.97 | — | — | |
| SCHEMBL7417330 | 0.90 | — | — | |
| SCHEMBL8315655 | 0.87 | — | — | |
| SCHEMBL8313569 | 0.87 | — | — | |
| SCHEMBL7416627 | 0.86 | — | — | |
| SCHEMBL7407216 | 0.84 | — | — | |
| SCHEMBL7415874 | 0.84 | — | — | |
| SCHEMBL7411100 | 0.84 | — | — | |
| SCHEMBL7413295 | 0.83 | — | — | |
| SCHEMBL7417180 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752991-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONES ANTAGONISTS OF AMPA AND NMDA RECEPTORS | RHONE POULENC RORER SA (FR) | 1999-05-26 | — | — | EP | claimed |