Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317730 | 0.89 | AVPR1A (0.47) | AVPR1AAVPR2 | |
| SCHEMBL8317444 | 0.87 | AVPR1A (0.48) | AVPR1AAVPR2 | |
| SCHEMBL8318476 | 0.86 | AVPR1A (0.54) | AVPR1AAVPR2 | |
| SCHEMBL8312861 | 0.84 | AVPR1A (0.45) | AVPR1AAVPR2 | |
| SCHEMBL8317993 | 0.84 | AVPR1A (0.47) | AVPR1AAVPR2 | |
| SCHEMBL8318194 | 0.81 | AVPR2 (0.54) | AVPR1AAVPR2 | |
| SCHEMBL8317926 | 0.81 | AVPR2 (0.61) | AVPR1AAVPR2 | |
| SCHEMBL8318185 | 0.80 | AVPR2 (0.59) | AVPR1AAVPR2 | |
| SCHEMBL7333390 | 0.80 | AVPR2 (0.62) | AVPR1AAVPR2 | |
| SCHEMBL8315819 | 0.80 | AVPR2 (0.52) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |