Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 12/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 12/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010651 | 1.00 | TOP2A (0.49) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL8323568 | 0.92 | TOP2A (0.57) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL8323564 | 0.92 | TOP2A (0.57) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7010327 | 0.90 | TOP2A (0.46) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL8322753 | 0.90 | TOP2A (0.46) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL8325246 | 0.90 | TOP2A (0.46) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7012465 | 0.90 | TOP2A (0.46) | TOP2ATOP2BKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7008547 | 0.89 | TOP2A (0.63) | TOP2ATOP2BKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL8319180 | 0.88 | CYP3A4 (0.45) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7009159 | 0.88 | CYP3A4 (0.45) | TOP2ATOP2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |