Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316199 | 0.91 | AVPR2 (0.53) | AVPR1AAVPR2 | |
| SCHEMBL8312663 | 0.88 | AVPR2 (0.52) | AVPR1AAVPR2 | |
| SCHEMBL8317342 | 0.86 | AVPR2 (0.53) | AVPR1AAVPR2 | |
| SCHEMBL8312327 | 0.85 | AVPR2 (0.49) | AVPR1AAVPR2 | |
| SCHEMBL8313614 | 0.85 | AVPR2 (0.50) | AVPR1AAVPR2 | |
| SCHEMBL8316971 | 0.83 | AVPR1A (0.54) | AVPR1ARAB9AAVPR2 | |
| SCHEMBL7339408 | 0.83 | AVPR2 (0.64) | AVPR1AAVPR2 | |
| SCHEMBL8316632 | 0.82 | AVPR2 (0.56) | AVPR1AAVPR2 | |
| SCHEMBL8317328 | 0.82 | AVPR2 (0.49) | AVPR1AAVPR2 | |
| SCHEMBL8318816 | 0.81 | AVPR2 (0.54) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |