Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317901 | 1.00 | POLB (0.45) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8317595 | 0.81 | TRPV1 (0.47) | POLBKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8317590 | 0.81 | TRPV1 (0.47) | POLBKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8321332 | 0.80 | PLK1 (0.44) | POLBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8321329 | 0.80 | PLK1 (0.44) | POLBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1689720 | 0.73 | HDAC3 (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1689721 | 0.73 | HDAC3 (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1689718 | 0.73 | HDAC3 (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8319358 | 0.72 | GRIN2D (0.40) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8319359 | 0.72 | GRIN2D (0.40) | POLBGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880162-A | INSECTICIDES FOR SOIL BORNE INSECT PESTS | BRITISH TECHNOLOGY GROUP, LTD. (GB) | 1999-03-09 | — | — | US | disclosed |
| EP-0757668-A1 | PESTICIDAL FLUOROOLEFINS | British Technology Group Ltd. (GB) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029887-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |