Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318551 | 1.00 | KDR (0.33) | KDRCYP1A2CYP3A4CYP2C19MET | |
| SCHEMBL8322194 | 0.83 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C19METMEN1 | |
| SCHEMBL8327963 | 0.81 | GAA (0.46) | CYP1A2METMEN1KMT2AGAA | |
| SCHEMBL8317077 | 0.80 | HPGD (0.39) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL8321139 | 0.80 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C19METMEN1 | |
| SCHEMBL8321138 | 0.80 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C19METMEN1 | |
| SCHEMBL8324746 | 0.80 | KDM4E (0.37) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL8321417 | 0.76 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19KMT2AGAA | |
| SCHEMBL8325590 | 0.75 | MAPT (0.47) | CYP1A2CYP3A4CYP2C19METMEN1 | |
| SCHEMBL8325596 | 0.75 | MAPT (0.47) | CYP1A2CYP3A4CYP2C19METMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |