Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318626 | 1.00 | FDFT1 (0.62) | FDFT1 | |
| SCHEMBL8318629 | 1.00 | FDFT1 (0.62) | FDFT1 | |
| Bicarbonate SCHEMBL9058633 | 0.97 | FDFT1 (0.59) | FDFT1 | |
| Bicarbonate SCHEMBL9058634 | 0.97 | FDFT1 (0.59) | FDFT1 | |
| Bicarbonate SCHEMBL9058632 | 0.97 | FDFT1 (0.59) | FDFT1 | |
| SCHEMBL8322243 | 0.92 | FDFT1 (0.64) | FDFT1 | |
| SCHEMBL8795996 | 0.92 | FDFT1 (0.60) | FDFT1 | |
| SCHEMBL8326808 | 0.92 | FDFT1 (0.74) | FDFT1 | |
| SCHEMBL8322228 | 0.92 | FDFT1 (0.64) | FDFT1 | |
| SCHEMBL8326806 | 0.92 | FDFT1 (0.74) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | claimed |
| EP-0782451-A1 | COMBINATION OF A CHOLESTEROL ABSORPTION INHIBITOR AND A CHOLESTEROL SYNTHESIS INHIBITOR | PFIZER INC. (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | claimed |
| WO-1996009827-A2 | COMBINATION OF A CHOLESTEROL ABSORPTION INHIBITOR AND A CHOLESTEROL SYNTHESIS INHIBITOR | PFIZER INC. (US) | 1996-04-04 | — | — | WO | claimed |
| US-5965553-A | Squalene synthetase inhibitors | PFIZER INC. (US) | 1999-10-12 | — | — | US | disclosed |
| US-5807834-A | ANTICHOLESTEROL AGENTS | PFIZER INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0814080-A1 | Squalene synthetase inhibitors | PFIZER INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0782451-A1 | COMBINATION OF A CHOLESTEROL ABSORPTION INHIBITOR AND A CHOLESTEROL SYNTHESIS INHIBITOR | PFIZER INC. (US) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | disclosed |
| WO-1996009827-A2 | COMBINATION OF A CHOLESTEROL ABSORPTION INHIBITOR AND A CHOLESTEROL SYNTHESIS INHIBITOR | PFIZER INC. (US) | 1996-04-04 | — | — | WO | disclosed |