Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322199 | 0.90 | PLA2G1B (1.00) | PLA2G1BPLA2G2A | |
| SCHEMBL7005496 | 0.83 | PLA2G1B (0.81) | PLA2G1BPLA2G2A | |
| SCHEMBL27458889 | 0.83 | PLA2G1B (0.79) | PLA2G1BPLA2G2A | |
| SCHEMBL9082778 | 0.82 | PLA2G1B (1.00) | PLA2G1BPLA2G2A | |
| SCHEMBL9080540 | 0.82 | PLA2G1B (0.84) | PLA2G1BPLA2G2A | |
| SCHEMBL7053618 | 0.80 | PLA2G1B (0.84) | PLA2G1BPLA2G2A | |
| SCHEMBL9082151 | 0.79 | PLA2G1B (0.72) | PLA2G1BPLA2G2A | |
| SCHEMBL9082372 | 0.78 | PLA2G1B (0.85) | PLA2G1BPLA2G2A | |
| SCHEMBL7011405 | 0.77 | PLA2G1B (1.00) | PLA2G1BPLA2G2A | |
| SCHEMBL8026443 | 0.75 | PLA2G1B (0.57) | PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772596-A4 | INDOLIZINE sPLA2 INHIBITORS | LILLY CO ELI (US) | 1999-01-13 | — | — | EP | disclosed |
| EP-0772596-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |