Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130596 | 0.89 | MAPK14 (0.75) | GCGRMAPK14 | |
| SCHEMBL2647090 | 0.89 | MAPK14 (0.75) | GCGRMAPK14 | |
| SCHEMBL8119445 | 0.89 | MAPK14 (0.75) | GCGRMAPK14 | |
| SCHEMBL2647264 | 0.81 | MAPK14 (0.77) | GCGRMAPK14 | |
| SCHEMBL8322278 | 0.80 | GCGR (0.77) | GCGRMAPK14 | |
| SCHEMBL8325951 | 0.80 | GCGR (0.74) | GCGRMAPK14 | |
| SCHEMBL2662940 | 0.79 | GCGR (0.97) | GCGRMAPK14 | |
| SCHEMBL8467312 | 0.77 | GCGR (0.80) | GCGRMAPK14 | |
| SCHEMBL8326739 | 0.76 | GCGR (0.81) | GCGRMAPK14 | |
| SCHEMBL4793206 | 0.75 | GCGR (0.65) | GCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871444-A4 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 1999-01-13 | — | — | EP | claimed |
| EP-0871444-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-10-21 | — | — | EP | claimed |
| WO-1997005878-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | claimed |
| US-5837719-A | USEFUL FOR TREATING CYTOKINE MEDIATED DISEASES, INFLAMMATION,SHOCK, ARTHRITIS, RESPIRATORY DISORDERS, THROMBOSIS, VIRAL INFECTION, GASTROINTESTINAL DISORDERS | MERCK & CO., INC. (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1997005878-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | disclosed |