Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320221 | 0.91 | HDAC3 (0.48) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8325021 | 0.86 | HDAC1 (0.64) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8319546 | 0.85 | HDAC1 (0.67) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8319220 | 0.84 | HDAC1 (0.62) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8323816 | 0.81 | HDAC1 (0.63) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8324562 | 0.81 | HDAC1 (0.60) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8324416 | 0.80 | HDAC1 (0.70) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8319323 | 0.80 | HDAC1 (0.73) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8325016 | 0.80 | HDAC1 (0.73) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL8324611 | 0.79 | HDAC1 (0.69) | HDAC1HDAC2HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |