Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647550 | 0.92 | GAA (0.38) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL31598447 | 0.92 | GAA (0.38) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21580871 | 0.92 | GAA (0.38) | GAANFKB1NFKB2RELABTK | |
| Hydrochloric Acid SCHEMBL23850393 | 0.91 | GAA (0.38) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21287726 | 0.88 | BTK (0.37) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21287164 | 0.88 | BTK (0.37) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21287163 | 0.87 | BTK (0.36) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL22814480 | 0.87 | BTK (0.36) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21287159 | 0.86 | BTK (0.39) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL21287439 | 0.86 | BTK (0.39) | GAANFKB1NFKB2RELABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911643-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| US-7750158-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750158-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| EP-0641339-B1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5407943-A | Azaspiro quinolone antibacterial agents | PFIZER INC. (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0641339-A1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992022550-A1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1992-12-23 | — | — | WO | disclosed |