Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902496 | 0.85 | KDM4E (0.47) | KDM4EMAPTTHRBDDB1CRBN | |
| SCHEMBL1813251 | 0.84 | MAPT (0.49) | KDM4EMAPTTHRBDDB1CRBN | |
| SCHEMBL1583251 | 0.80 | DDB1 (0.47) | KDM4EMAPTTHRBDDB1CRBN | |
| SCHEMBL3410150 | 0.79 | MAPT (0.49) | KDM4EMAPTTHRBDDB1CRBN | |
| SCHEMBL17128329 | 0.79 | HPGD (0.62) | KDM4EMAPTTHRBHPGDGPR119 | |
| SCHEMBL994288 | 0.79 | HPGD (0.58) | KDM4EMAPTTHRBHPGDGPR119 | |
| SCHEMBL30830594 | 0.78 | DDB1 (0.57) | KDM4EMAPTTHRBDDB1CRBN | |
| SCHEMBL2165760 | 0.78 | HPGD (0.50) | KDM4EMAPTTHRBHPGDGPR119 | |
| SCHEMBL24267253 | 0.77 | HPGD (0.53) | KDM4EMAPTTHRBHPGDGPR119 | |
| SCHEMBL5514832 | 0.77 | HPGD (0.65) | HPGDGPR119RECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5814636-A | TREATMENT AND PROPHYLAXIS OF THROMBOTIC DISEASES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0721941-A1 | NOVEL COMPOUND HAVING PLATELET AGGREGATION INHIBITOR EFFECT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1996-07-17 | — | — | EP | disclosed |