Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10291941 | 0.96 | KMT2A (0.75) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7100273 | 0.95 | KMT2A (0.72) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL24605352 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL27947111 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2741099 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12370833 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL26038796 | 0.90 | KMT2A (0.66) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL21185911 | 0.87 | HTT (0.61) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| Cyclohexane Carboxamide SCHEMBL21771917 | 0.87 | KMT2A (0.62) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL13612593 | 0.86 | HTT (0.59) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |