Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326239 | 0.90 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8611310 | 0.87 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8322018 | 0.87 | ADORA2A (0.88) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL239667 | 0.86 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4371630 | 0.86 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL242090 | 0.86 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5723583 | 0.86 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4431832 | 0.86 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4371641 | 0.86 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8608927 | 0.86 | ADORA2A (0.82) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |