Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268687 | 0.90 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4823813 | 0.88 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8313787 | 0.88 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4823814 | 0.88 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL825369 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4820946 | 0.79 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4820951 | 0.79 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8313280 | 0.79 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8315588 | 0.78 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8313277 | 0.78 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |