Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614516 | 0.86 | KMT2A (0.53) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL4626706 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL4627652 | 0.84 | HDAC8 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2033537 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL4627896 | 0.84 | HDAC1 (0.54) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL4627898 | 0.84 | HDAC1 (0.54) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL4627655 | 0.84 | HDAC8 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2032563 | 0.81 | GAA (0.64) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL4628354 | 0.77 | HDAC8 (0.60) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL4628357 | 0.77 | HDAC8 (0.60) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179832-B2 | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2007-02-20 | — | — | US | disclosed |
| US-7179832-B2 | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2007-02-20 | — | — | US | disclosed |
| WO-2004065370-A1 | GLYCOGEN SYNTHASE KINASE 3BETA INHIBITOR, COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CRYSTALGENOMICS, INC. (KR) | 2004-08-05 | — | — | WO | disclosed |