Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488098 | 1.00 | PARP1 (0.60) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL14027180 | 0.77 | PARP1 (0.62) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL307689 | 0.77 | PARP1 (0.62) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL17697552 | 0.76 | PARP1 (0.61) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1536658 | 0.75 | PARP1 (0.60) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL2172575 | 0.75 | PARP1 (1.00) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29519573 | 0.75 | PARP1 (1.00) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL12463821 | 0.75 | PARP1 (0.60) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL31743106 | 0.75 | PARP1 (0.60) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29492688 | 0.75 | PARP1 (1.00) | PARP1CYP1A2ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12338486-B2 | Single-stranded break detection in double-stranded DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-06-24 | — | — | US | claimed |
| EP-3781711-B1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INST TECHNOLOGY (US) | 2024-11-20 | — | — | EP | claimed |
| US-11505827-B2 | Systems and methods for determining genetic data | Roche Sequencing Solutions, Inc. (US) | 2022-11-22 | — | — | US | claimed |
| US-20210071240-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-11 | — | — | US | claimed |
| EP-3781711-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-02-24 | — | — | EP | claimed |
| WO-2019204585-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-24 | — | — | WO | claimed |
| US-20190292591-A1 | SYSTEMS AND METHODS FOR DETERMINING GENETIC DATA | Genia Technologies, Inc. (US) | 2019-09-26 | — | — | US | claimed |
| US-10260093-B2 | Systems and methods for determining genetic data | Genia Technologies, Inc. (US) | 2019-04-16 | — | — | US | claimed |
| US-9725474-B2 | Modified nucleic acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-08 | — | — | US | claimed |
| US-20140303032-A1 | SYSTEMS AND METHODS FOR DETERMINING GENETIC DATA | Roche Sequencing Solutions, Inc. | 2014-10-09 | — | — | US | claimed |
| US-7374882-B2 | Method for base sequencing and biologically active nucleic acids | RIKEN (JP) | 2008-05-20 | — | — | US | claimed |
| WO-2007137000-A2 | COMBINATION CANCER CHEMOTHERAPY | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2007-11-29 | — | — | WO | claimed |
| US-20040115665-A1 | Method for base sequencing and biologically active nucleic acids | RIKEN (JP) | 2004-06-17 | — | — | US | claimed |
| JP-2004514440-A | — | — | 2004-05-20 | — | — | JP | claimed |
| US-20040077004-A1 | Use of nucleotide analogs in the analysis of oligonucleotide mixtures and highly multiplexed nucleic acid sequencing | TRUSTEES OF BOSTON UNIVERSITY, THE | 2004-04-22 | — | — | US | claimed |
| US-6660229-B2 | Synthesizing extension products of the target nucleic acid in the presence of chain terminating nucleotides and mass-matched nucleotides; determining the mass of each extension product; and calculating a mass shift | THE TRUSTEES OF BOSTON UNIVERSITY | 2003-12-09 | — | — | US | claimed |
| EP-1348035-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | Riken (JP) | 2003-10-01 | — | — | EP | claimed |
| WO-2002044195-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | RIKEN (JP) | 2002-06-06 | — | — | WO | claimed |
| EP-0355750-B1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER LAMBERT CO (US) | 1995-01-25 | — | — | EP | claimed |
| EP-0355750-A1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER-LAMBERT COMPANY (US) | 1990-02-28 | — | — | EP | claimed |