Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268753 | 0.93 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8268694 | 0.91 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8268700 | 0.89 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8268724 | 0.86 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8269869 | 0.86 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL4821526 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL14349624 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8268720 | 0.85 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8270581 | 0.85 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8271325 | 0.84 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |