SCHEMBL8322393

SCHEMBL8322393

NC(=O)C1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ICAM1 P05362 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6749076 0.83 ICAM1 (1.00) ICAM1
SCHEMBL6750173 0.82 ICAM1 (0.75) ICAM1
SCHEMBL6752097 0.82 ICAM1 (0.74) ICAM1
SCHEMBL6750460 0.82 ICAM1 (0.84) ICAM1
SCHEMBL6750454 0.82 ICAM1 (0.70) ICAM1
SCHEMBL7147245 0.81 ICAM1 (0.72) ICAM1
SCHEMBL6745248 0.81 ICAM1 (0.68) ICAM1
SCHEMBL6750107 0.81 ICAM1 (0.84) ICAM1
SCHEMBL6750396 0.81 ICAM1 (0.80) ICAM1
SCHEMBL6745646 0.80 ICAM1 (0.76) ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934941-A1 BENZOPIPERIDINE DERIVATIVES Eisai Co., Ltd. (JP) 1999-08-11 EP disclosed