Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428765 | 0.90 | MAPT (0.53) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2092356 | 0.85 | MAPT (0.56) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20984125 | 0.84 | HTT (0.58) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5809000 | 0.83 | MAPT (0.54) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2092353 | 0.83 | MAPT (0.54) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7416456 | 0.83 | NPC1 (0.57) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL20984140 | 0.82 | MAPT (0.53) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30358959 | 0.82 | MAPT (0.61) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7008397 | 0.82 | MAPT (0.53) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4073968 | 0.82 | NPC1 (0.55) | MAPTGAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | disclosed |