Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8852562 | 0.98 | GAA (0.43) | ADRA2AADRA2BADRA2CADRA1APOLB | |
| SCHEMBL17887757 | 0.94 | NISCH (0.47) | ADRA2AADRA2BADRA2CADRA1APOLB | |
| SCHEMBL9056993 | 0.94 | NISCH (0.47) | ADRA2AADRA2BADRA2CADRA1APOLB | |
| Hydrochloric Acid SCHEMBL8327692 | 0.92 | NISCH (0.46) | ADRA2AADRA2BADRA2CADRA1APOLB | |
| SCHEMBL17887578 | 0.76 | NISCH (0.43) | ADRA2AADRA2BADRA2CNISCHGAA | |
| SCHEMBL17887813 | 0.76 | NISCH (0.43) | ADRA2AADRA2BADRA2CNISCHGAA | |
| SCHEMBL17887666 | 0.76 | PIM1 (0.41) | ADRA2AADRA2BADRA2CADRA1ANISCH | |
| SCHEMBL11010223 | 0.69 | — | — | |
| SCHEMBL16362113 | 0.69 | CYP2D6 (0.47) | POLBCYP2D6GAAGFERALOX15 | |
| SCHEMBL25400969 | 0.67 | KDM4E (0.43) | ADRA2AADRA2BADRA2CADRA1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789571-A4 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO INC (US) | 1999-04-14 | — | — | EP | claimed |
| EP-0789571-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | Merck & Co., Inc. (US) | 1997-08-20 | — | — | EP | claimed |
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | claimed |
| EP-0069295-B1 | PROCESS FOR THE MANUFACTURE OF POSSIBLY CELLULAR POLYURETHANE OR POLYURETHANE-POLYUREA MOULDED ARTICLES | BASF Aktiengesellschaft (DE) | 1986-05-21 | — | — | EP | disclosed |
| EP-0069295-A1 | Process for the manufacture of possibly cellular polyurethane or polyurethane-polyurea moulded articles | BASF Aktiengesellschaft (DE) | 1983-01-12 | — | — | EP | disclosed |