Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326202 | 0.85 | EDNRB (0.74) | EDNRAEDNRB | |
| SCHEMBL8323184 | 0.84 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL8319563 | 0.84 | EDNRB (0.74) | EDNRAEDNRB | |
| SCHEMBL8326954 | 0.82 | EDNRB (0.74) | EDNRAEDNRB | |
| Benzamide SCHEMBL7585785 | 0.82 | EDNRA (0.85) | EDNRAEDNRB | |
| SCHEMBL30057758 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL2678965 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8328452 | 0.81 | EDNRB (0.70) | EDNRAEDNRB | |
| SCHEMBL8328448 | 0.81 | EDNRB (0.70) | EDNRAEDNRB | |
| SCHEMBL8326190 | 0.81 | EDNRB (0.79) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | claimed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |