SCHEMBL8323494

SCHEMBL8323494

C=CC(=O)NC(O)C(=O)OC.C=CC(=O)NCO

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
TGM2 P21980 5/20 0.33
PSMB5 P28074 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
ACACB O00763 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683866 0.88 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL23036092 0.86 TSHR (0.36) TSHRALDH1A1MAPK1TDP1
Methoxymethane SCHEMBL450335 0.86 TSHR (0.50) TSHRALDH1A1MAPK1TDP1TGM2
Ether SCHEMBL9262685 0.81 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9000788 0.80 TSHR (0.41) TSHRALDH1A1MAPK1TDP1TAS1R3
Methoxymethane SCHEMBL422310 0.80 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9257784 0.79 TSHR (0.40) TSHRALDH1A1MAPK1TDP1ZDHHC20
Methane SCHEMBL27684800 0.78
SCHEMBL28485989 0.77 TSHR (0.72) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9000275 0.76 TSHR (0.45) TSHRALDH1A1ZDHHC20ZDHHC2TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981648-A CURABLE LATEX COMPOSITION COMPRISING AN EMULSION IN AN AQUEOUS MEDIUM; DOES NOT LIBERATE FORMALDEHYDE ON CURING; COATINGS AL CHEM & CY US ACQUICO, INC. 1999-11-09 US disclosed