SCHEMBL8323650

SCHEMBL8323650

COCCCCCc1nc2c(N)nc3ccccc3c2n1CC(C)C

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 18/20 0.61
TLR8 Q9NR97 7/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646771 0.91 TLR7 (0.62) TLR7TLR8
SCHEMBL5130384 0.87 TLR7 (0.69) TLR7TLR8
Hydrochloric Acid SCHEMBL5459009 0.86 TLR7 (0.68) TLR7TLR8
SCHEMBL6246349 0.86 TLR7 (0.73) TLR7TLR8
Hydrochloric Acid SCHEMBL1302099 0.85 TLR7 (0.72) TLR7TLR8
SCHEMBL6723566 0.85 TLR7 (0.65) TLR7TLR8
SCHEMBL9385722 0.84 TLR7 (0.54) TLR7TLR8
SCHEMBL1301722 0.83 TLR7 (0.72) TLR7TLR8
SCHEMBL13533456 0.82 TLR7 (0.65) TLR7TLR8
SCHEMBL3872728 0.81 TLR7 (0.71) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582581-B1 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES MINNESOTA MINING & MFG (US) 1999-05-06 EP claimed