Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 7/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DNM2 | P50570 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326103 | 0.86 | SOAT1 (0.47) | SOAT1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8325945 | 0.86 | SOAT1 (0.47) | SOAT1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8317765 | 0.86 | SOAT1 (0.47) | SOAT1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8325263 | 0.84 | SOAT1 (0.42) | SOAT1GPR84GAAHTTSMN1; SMN2 | |
| SCHEMBL9000483 | 0.83 | SOAT1 (0.41) | SOAT1GPR84GAATDP1L3MBTL1 | |
| SCHEMBL9000801 | 0.83 | SOAT1 (0.41) | SOAT1GPR84GAATDP1L3MBTL1 | |
| SCHEMBL9000736 | 0.83 | SOAT1 (0.41) | SOAT1GPR84GAATDP1L3MBTL1 | |
| SCHEMBL9000882 | 0.83 | SOAT1 (0.41) | SOAT1GPR84GAATDP1L3MBTL1 | |
| SCHEMBL9000921 | 0.83 | SOAT1 (0.41) | SOAT1GPR84GAATDP1L3MBTL1 | |
| SCHEMBL8321429 | 0.82 | SOAT1 (0.35) | SOAT1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609960-B1 | New N-heteroarylamide derivatives as inhibitors of acyl coenzyme A: cholestrol acyl transferase | PFIZER (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5656634-A | N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0609960-A1 | New N-heteroarylamide derivatives as inhibitors of acyl coenzyme A: cholestrol acyl transferase | PFIZER INC. (US) | 1994-08-10 | — | — | EP | disclosed |