Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 15/20 | 0.76 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.76 |
| ▸ | OXTR | P30559 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5101528 | 0.99 | AVPR1A (0.75) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727376 | 0.91 | AVPR2 (0.79) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL8325451 | 0.90 | AVPR1A (0.79) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727306 | 0.90 | AVPR1A (0.79) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL14032644 | 0.89 | AVPR1A (0.75) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727430 | 0.89 | AVPR1A (0.75) | AVPR1AAVPR2KCNH2OXTR | |
| Hydrochloric Acid SCHEMBL5098055 | 0.88 | AVPR1A (0.74) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727440 | 0.87 | AVPR2 (0.79) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL8325142 | 0.87 | AVPR1A (0.72) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL5095191 | 0.87 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| WO-2004074291-A1 | TRIAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2004-09-02 | — | — | WO | disclosed |