Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.59 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.59 |
| ▸ | CTSD | P07339 | 2/20 | 0.54 |
| ▸ | CTSE | P14091 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369536 | 0.89 | BACE1 (0.60) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5372747 | 0.85 | BACE1 (0.59) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5372756 | 0.84 | BACE1 (0.58) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5241603 | 0.84 | BACE1 (0.63) | BACE1BACE2CTSDCTSE | |
| SCHEMBL4896633 | 0.84 | BACE1 (0.63) | BACE1BACE2CTSDCTSE | |
| SCHEMBL14425943 | 0.83 | BACE1 (0.57) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5372394 | 0.83 | BACE1 (0.57) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5367359 | 0.83 | BACE1 (0.58) | BACE1BACE2CTSDCTSE | |
| SCHEMBL14426005 | 0.83 | BACE1 (0.58) | BACE1BACE2CTSDCTSE | |
| SCHEMBL14425947 | 0.83 | BACE1 (0.58) | BACE1BACE2CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |