Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 0.55 |
| ▸ | PRKCG | P05129 | 5/20 | 0.55 |
| ▸ | PRKCB | P05771 | 5/20 | 0.55 |
| ▸ | PRKCA | P17252 | 5/20 | 0.55 |
| ▸ | PRKCH | P24723 | 5/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.55 |
| ▸ | PRKACA | P17612 | 4/20 | 0.55 |
| ▸ | PRKACG | P22612 | 4/20 | 0.55 |
| ▸ | PRKACB | P22694 | 4/20 | 0.55 |
| ▸ | PHKG2 | P15735 | 3/20 | 0.55 |
| ▸ | PRKCI | P41743 | 3/20 | 0.55 |
| ▸ | PHKA2 | P46019 | 3/20 | 0.55 |
| ▸ | PHKA1 | P46020 | 3/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.55 |
| ▸ | PHKG1 | Q16816 | 3/20 | 0.55 |
| ▸ | PHKB | Q93100 | 3/20 | 0.55 |
| ▸ | MYLK | Q15746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8324110 | 1.00 | PRKD3 (0.55) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8327160 | 0.91 | PRKD3 (0.64) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8327156 | 0.91 | PRKD3 (0.64) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8327163 | 0.91 | PRKD3 (0.64) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Trifluoroacetic Acid SCHEMBL8329483 | 0.90 | PRKD3 (0.69) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Trifluoroacetic Acid SCHEMBL8329487 | 0.90 | PRKD3 (0.69) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Acetic Acid SCHEMBL8325302 | 0.83 | PRKD3 (0.72) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Acetic Acid SCHEMBL9394907 | 0.83 | PRKD3 (0.72) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8322489 | 0.81 | PRKD3 (0.81) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8326455 | 0.81 | PRKD3 (0.81) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470490-B1 | Substituted pyrroles | HOFFMANN LA ROCHE (CH) | 1999-05-06 | — | — | EP | disclosed |
| US-5292747-A | Substituted pyrroles | HOFFMAN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0470490-A1 | Substituted pyrroles | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-12 | — | — | EP | disclosed |