Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100785 | 1.00 | KMT2A (0.49) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL5110832 | 0.94 | KMT2A (0.43) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL5104007 | 0.91 | KMT2A (0.44) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL5099630 | 0.91 | TDP1 (0.47) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL2990960 | 0.91 | TDP1 (0.47) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL2990956 | 0.91 | TDP1 (0.47) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL5111248 | 0.89 | HRH4 (0.41) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL2992896 | 0.87 | MEN1 (0.43) | KMT2AMEN1GAAHRH4HRH3 | |
| SCHEMBL5100644 | 0.87 | KMT2A (0.44) | KMT2AMEN1HRH4HRH3F10 | |
| SCHEMBL5103713 | 0.87 | S1PR3 (0.49) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |