Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775380 | 0.98 | CYP1A2 (0.70) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL10616011 | 0.88 | CYP1A2 (0.57) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8431787 | 0.82 | CYP1A2 (0.75) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL9640545 | 0.81 | CYP1A2 (1.00) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL3791688 | 0.81 | CYP1A2 (0.72) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL2702801 | 0.81 | CYP1A2 (0.72) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL2703472 | 0.79 | CYP1A2 (0.70) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL8303247 | 0.79 | CYP1A2 (0.70) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL9456287 | 0.79 | CYP1A2 (0.59) | CYP1A2MAPTKMT2ATP53GLA | |
| SCHEMBL12719643 | 0.78 | CYP1A2 (0.68) | CYP1A2MAPTKMT2ATP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916660-A2 | Process for the production of sulphonylurea salts | Novartis AG (CH) | 1999-05-19 | — | — | EP | disclosed |