Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327535 | 0.89 | HDAC1 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8326528 | 0.88 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8326311 | 0.88 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8327646 | 0.88 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8326655 | 0.88 | HDAC1 (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8327500 | 0.86 | HDAC1 (0.44) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8325172 | 0.86 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8326565 | 0.86 | HDAC3 (0.43) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8325208 | 0.85 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8324337 | 0.85 | HDAC1 (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |