Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682380 | 1.00 | AHR (0.45) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL5682382 | 1.00 | AHR (0.45) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL11353943 | 0.88 | KCNH2 (0.42) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL7900634 | 0.86 | KCNH2 (0.41) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL7900632 | 0.86 | KCNH2 (0.41) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL2080531 | 0.82 | AHR (0.48) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL2080529 | 0.82 | AHR (0.48) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL12783928 | 0.82 | AHR (0.48) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| SCHEMBL9661512 | 0.80 | AHR (0.46) | AHRGRIK1GRIK2GRIK3CYP1A2 | |
| Hydrochloric Acid SCHEMBL11476726 | 0.80 | AHR (0.46) | AHRGRIK1GRIK2GRIK3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |