Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.61 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.61 |
| ▸ | CTSD | P07339 | 2/20 | 0.58 |
| ▸ | CTSE | P14091 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454588 | 1.00 | BACE1 (0.61) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5367907 | 0.93 | BACE1 (0.65) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5367912 | 0.93 | BACE1 (0.65) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5374149 | 0.93 | BACE1 (0.65) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5374102 | 0.93 | BACE1 (0.62) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5372778 | 0.92 | BACE1 (0.63) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5367440 | 0.92 | BACE1 (0.63) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5372764 | 0.91 | BACE1 (0.59) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5365649 | 0.91 | BACE1 (0.64) | BACE1BACE2CTSDCTSE | |
| SCHEMBL5369546 | 0.91 | BACE1 (0.67) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262208-B2 | Hydroxypropyl amides for the treatment of Alzheimer's disease | ELAN PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262208-B2 | Hydroxypropyl amides for the treatment of Alzheimer's disease | ELAN PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |