⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303742 | 0.73 | — | — | |
| SCHEMBL8774030 | 0.67 | — | — | |
| SCHEMBL137542 | 0.65 | — | — | |
| SCHEMBL136344 | 0.65 | — | — | |
| SCHEMBL3276103 | 0.65 | — | — | |
| SCHEMBL8185875 | 0.65 | — | — | |
| SCHEMBL4967707 | 0.58 | — | — | |
| SCHEMBL81839 | 0.58 | — | — | |
| SCHEMBL11183068 | 0.58 | — | — | |
| SCHEMBL6065835 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207766-A1 | NOVEL SULFAMATE COMPOUNDS FOR MEDICAL USE | Abbott Products GmbH (DE) | 2010-07-21 | — | — | EP | claimed |
| WO-2009050252-A1 | NOVEL SULFAMATE COMPOUNDS FOR MEDICAL USE | SOLVAY PHARMACEUTICALS GMBH (DE) | 2009-04-23 | — | — | WO | claimed |
| US-20090104126-A1 | Sulfamate Compounds and Uses Thereof | SOLVAY PHARMACEUTICALS GMBH (DE) | 2009-04-23 | — | — | US | claimed |
| EP-1477485-A1 | Aminophenol derivatives | Bayer CropScience AG (DE) | 2004-11-17 | — | — | EP | claimed |
| EP-0934302-B1 | AMINOPHENOL DERIVATES | BAYER CROPSCIENCE AG (DE) | 2004-08-25 | — | — | EP | claimed |
| US-6194443-B1 | Aminophenol derivatives with fungicidal property | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |
| EP-0934302-A2 | AMINOPHENOL DERIVATES | BAYER AG (DE) | 1999-08-11 | — | — | EP | claimed |
| WO-1998016522-A2 | AMINOPHENOL DERIVATES WITH FUNGICIDAL PROPERTY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-23 | — | — | WO | claimed |
| EP-0421752-A2 | Substituted acrylamido-penicillanic acid derivatives | Beecham Group p.l.c. (GB) | 1991-04-10 | — | — | EP | claimed |
| US-20180222905-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9938269-B2 | Inhibitor compounds of phosphodiesterase type 10A | ABBVIE INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-9657034-B2 | Substituted furo[3,2-c]pyridines, thieno[3,2-c]pyridines, thieno[2,3-d]pyridazines and pyrido[3,4-d]pyridazines as phosphodiesterase type 10A inhibitors | AbbVie Deuschland GmbH & Co. KG (DE) | 2017-05-23 | — | — | US | disclosed |
| EP-2970328-B1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE DEUTSCHLAND (DE) | 2017-04-26 | — | — | EP | disclosed |
| EP-2776418-B1 | INHIBITORS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE DEUTSCHLAND (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-4525475-A | Prevention of thrombolic disorder with imidazole derivatives and salts thereof | THOROGOOD PETER B (GB) | 1985-06-25 | — | — | US | disclosed |
| EP-0097127-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | disclosed |
| US-4328234-A | Imidazole derivatives and salts thereof and pharmaceutical formulations useful in thrombo-embolic disorders | BURROUGHS WELLCOME CO. (US) | 1982-05-04 | — | — | US | disclosed |
| US-3991199-A | ANALGESICS AND SEDATIVES | ENDO LABORATORIES, INC. (US) | 1976-11-09 | — | — | US | disclosed |
| US-3970654-A | Antiviral 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-07-20 | — | — | US | disclosed |