Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702462 | 0.85 | TACR1 (0.71) | TACR1 | |
| SCHEMBL8702464 | 0.85 | TACR1 (0.71) | TACR1 | |
| SCHEMBL8702468 | 0.85 | TACR1 (0.71) | TACR1 | |
| SCHEMBL8522905 | 0.82 | TACR1 (0.53) | TACR1 | |
| SCHEMBL8522904 | 0.82 | TACR1 (0.53) | TACR1 | |
| SCHEMBL8326300 | 0.80 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8326297 | 0.80 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8322160 | 0.79 | TACR1 (0.71) | TACR1 | |
| SCHEMBL8322164 | 0.79 | TACR1 (0.71) | TACR1 | |
| SCHEMBL8326323 | 0.79 | TACR1 (0.70) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858444-A4 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0858444-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014671-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |