⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610516 | 1.00 | — | — | |
| SCHEMBL1706462 | 1.00 | — | — | |
| SCHEMBL2421634 | 0.93 | MAPT (0.95) | — | |
| SCHEMBL7795425 | 0.93 | MAPT (0.95) | — | |
| SCHEMBL6253494 | 0.93 | MAPT (0.95) | — | |
| SCHEMBL337289 | 0.91 | MAPT (1.00) | — | |
| SCHEMBL337879 | 0.91 | MAPT (1.00) | — | |
| SCHEMBL338043 | 0.91 | MAPT (1.00) | — | |
| SCHEMBL7461276 | 0.91 | MAPT (1.00) | — | |
| SCHEMBL21808105 | 0.91 | MAPT (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325236-A | — | — | None | — | — | JP | disclosed |
| JP-2025451-A | — | — | None | — | — | JP | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| JP-H08325236-A | OPTICALLY ACTIVE COMPOUND | F HOFFMANN LA ROCHE AG | 1996-12-10 | — | — | JP | disclosed |
| US-5518653-A | LIQUID CRYSTAL | HOFFMANN-LA ROCHE INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5166174-A | For duodenal ulcers or gastric ulcers | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0284180-B1 | PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-5100577-A | FERROELECTRIC LIQUID CRYSTAL MIXTURES AND COMPOUNDS AS WELL AS ELECTRO-OPTICAL DEVICES EMPLOYING SAME | HOFFMAN-LA ROCHE INC. (US) | 1992-03-31 | — | — | US | disclosed |
| US-4898455-A | Pyridine liquid crystalline compounds | HOFFMANN-LA ROCHE INC. (US) | 1990-02-06 | — | — | US | disclosed |
| JP-H0225451-A | CYCLOHEXYL ALPHA-FLUOROCARBOXYLATE | F HOFFMANN LA ROCHE AG | 1990-01-26 | — | — | JP | disclosed |
| EP-0343487-A1 | Cyclohexyl esters of alpha-fluoro/carboxylic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| EP-0284180-A1 | Prostaglandins E and anti ulcers containing same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-28 | — | — | EP | disclosed |