Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322064 | 0.90 | DRD4 (0.51) | DRD4DRD2 | |
| SCHEMBL8326767 | 0.89 | DRD4 (0.47) | DRD4DRD3 | |
| SCHEMBL8322798 | 0.89 | DRD4 (0.48) | DRD4DRD2DRD3 | |
| SCHEMBL8323338 | 0.88 | DRD4 (0.43) | DRD4DRD2DRD3 | |
| SCHEMBL8327166 | 0.88 | DRD4 (0.47) | DRD4DRD2 | |
| SCHEMBL8325386 | 0.88 | DRD4 (0.40) | DRD4DRD2DRD3 | |
| SCHEMBL8327695 | 0.87 | DRD4 (0.47) | DRD4DRD2DRD3 | |
| SCHEMBL8328227 | 0.83 | KMT2A (0.48) | — | |
| SCHEMBL8327701 | 0.80 | DRD4 (0.48) | DRD4DRD2DRD3 | |
| SCHEMBL8326456 | 0.80 | DRD4 (0.49) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |