Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346489 | 0.89 | CYP2C19 (0.62) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL9584558 | 0.84 | CYP2C19 (0.56) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL28744154 | 0.84 | CYP2C19 (0.56) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL7275819 | 0.84 | CYP2C19 (0.56) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL28672259 | 0.81 | CYP2C19 (0.53) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL1766985 | 0.80 | CYP2C19 (1.00) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL654985 | 0.80 | POLB (0.66) | CYP2C19POLBTDP1TAAR1NPC1 | |
| SCHEMBL11836175 | 0.80 | CYP2C19 (0.51) | CYP2C19SLC1A3SLC1A2SLC1A1POLB | |
| SCHEMBL8332586 | 0.80 | SMN1; SMN2 (0.48) | CYP2C19POLBTDP1NPC1RAB9A | |
| SCHEMBL6753453 | 0.79 | CYP2C19 (0.54) | CYP2C19SLC1A3SLC1A2SLC1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |