Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324205 | 0.91 | TACR1 (0.83) | TACR1 | |
| SCHEMBL8700774 | 0.90 | TACR1 (0.82) | TACR1 | |
| SCHEMBL8323801 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8701447 | 0.88 | TACR1 (0.81) | TACR1 | |
| SCHEMBL5216139 | 0.87 | TACR1 (0.82) | TACR1 | |
| SCHEMBL8468887 | 0.84 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8328566 | 0.81 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8323634 | 0.77 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8326759 | 0.76 | TACR1 (0.73) | TACR1 | |
| SCHEMBL8462009 | 0.76 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858444-A4 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0858444-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997014671-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |