⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043123 | 0.61 | — | — | |
| SCHEMBL1150832 | 0.60 | — | — | |
| SCHEMBL15016121 | 0.56 | — | — | |
| SCHEMBL17310406 | 0.55 | — | — | |
| SCHEMBL1426403 | 0.47 | — | — | |
| SCHEMBL2004962 | 0.47 | — | — | |
| SCHEMBL10017669 | 0.46 | — | — | |
| SCHEMBL194486 | 0.37 | — | — | |
| SCHEMBL15029211 | 0.37 | — | — | |
| SCHEMBL18773169 | 0.34 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296306-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2022-11-09 | — | — | EP | disclosed |
| EP-2816053-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2021-03-24 | — | — | EP | disclosed |
| CN-106977567-B | Oligonucleotide with protected base moiety | 味之素株式会社 | 2021-02-02 | — | — | CN | disclosed |
| EP-3296306-A1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO CO., INC. (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9371353-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20150080565-A1 | OLIGONUCLEOTIDE WITH PROTECTED BASE | AJINOMOTO CO., INC. (JP) | 2015-03-19 | — | — | US | disclosed |
| EP-2816053-A1 | BASE-PROTECTED OLIGONUCLEOTIDE | Ajinomoto Co., Inc. (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-8846885-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| US-20130267697-A1 | OLIGONUCLEOTIDE WITH PROTECTED BASE | AJINOMOTO CO., INC. (JP) | 2013-10-10 | — | — | US | disclosed |
| US-8143254-B2 | Methods for modulating ion channels | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090005386-A1 | Methods for Modulating Ion Channels | PACE UNIVERSITY | 2009-01-01 | — | — | US | disclosed |
| WO-2006089168-A2 | METHODS FOR MODULATING ION CHANNELS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-08-24 | — | — | WO | disclosed |