⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847107 | 0.92 | — | — | |
| SCHEMBL14980268 | 0.92 | — | — | |
| SCHEMBL16801194 | 0.92 | — | — | |
| SCHEMBL17301086 | 0.92 | — | — | |
| SCHEMBL17681570 | 0.91 | — | — | |
| SCHEMBL832606 | 0.79 | ATM (0.32) | — | |
| SCHEMBL20848344 | 0.77 | POLB (0.40) | — | |
| SCHEMBL16789759 | 0.77 | — | — | |
| SCHEMBL14979132 | 0.76 | ATM (0.31) | — | |
| SCHEMBL663921 | 0.76 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036912-A | Cytokine conjugates for the treatment of proliferative and infectious diseases | 辛索克斯公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12521437-B2 | IL-2 conjugates and methods of use thereof | Synthorx, Inc. (US) | 2026-01-13 | — | — | US | disclosed |
| US-12491254-B2 | Interleukin 10 conjugates and uses thereof | Synthorx, Inc. (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250325632-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250325633-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | disclosed |
| EP-3876973-B1 | INTERLEUKIN 10 CONJUGATES AND USES THEREOF | SYNTHORX INC (US) | 2025-10-22 | — | — | EP | disclosed |
| US-12377131-B2 | Cytokine conjugates for the treatment of autoimmune diseases | Synthorx, Inc. (US) | 2025-08-05 | — | — | US | disclosed |
| US-12318431-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | Synthorx, Inc. (US) | 2025-06-03 | — | — | US | disclosed |
| US-20250154218-A1 | IL-2 Conjugates and Methods of Use to Treat Autoimmune Diseases | Synthorx, Inc. (US) | 2025-05-15 | — | — | US | disclosed |
| EP-4547702-A1 | IL-21 POLYPEPTIDES AND METHODS OF USE | Beijing Neox Biotech Limited (CN) | 2025-05-07 | — | — | EP | disclosed |
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| WO-2011136872-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORP. (US) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011136872-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORP. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110182996-A1 | SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110182996-A1 | SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-07-28 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |