Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294305 | 0.87 | EDNRB (0.71) | EDNRAEDNRB | |
| SCHEMBL31559141 | 0.87 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL31559142 | 0.87 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL627598 | 0.87 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL7297111 | 0.87 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL7306773 | 0.87 | EDNRA (0.57) | EDNRAEDNRB | |
| Potassium SCHEMBL31559138 | 0.86 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL629196 | 0.86 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL8326434 | 0.86 | EDNRA (0.53) | EDNRAEDNRB | |
| Dimethyl Sulfoxide SCHEMBL627619 | 0.83 | EDNRA (0.66) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |