Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656180 | 0.89 | TSHR (0.62) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL4586246 | 0.84 | TSHR (0.56) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7049974 | 0.82 | TSHR (0.55) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL4586250 | 0.82 | TSHR (0.65) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7758238 | 0.82 | TSHR (0.55) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7057603 | 0.81 | TSHR (0.58) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL3157211 | 0.81 | IDO1 (0.61) | TSHRIDO1LOXL2AKR1C3ALDH1A1 | |
| SCHEMBL1165330 | 0.79 | TSHR (0.51) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL839828 | 0.79 | TSHR (0.64) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7931694 | 0.78 | IDO1 (0.53) | TSHRIDO1AKR1C3ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866700-A | Solid-phase synthesis of oligoribonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |