Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330564 | 0.80 | KMT2A (0.52) | KMT2AAAK1LMNASMN1; SMN2IDO1 | |
| SCHEMBL27955859 | 0.76 | BCHE (0.48) | LMNASMN1; SMN2BCHEALDH1A1POLB | |
| SCHEMBL6304376 | 0.76 | TSHR (0.59) | KMT2AAAK1LMNASMN1; SMN2IDO1 | |
| SCHEMBL8330091 | 0.76 | TSHR (0.59) | KMT2AAAK1LMNASMN1; SMN2IDO1 | |
| SCHEMBL10721862 | 0.75 | IDO1 (0.49) | KMT2ALMNASMN1; SMN2IDO1BCHE | |
| SCHEMBL3449356 | 0.75 | KMT2A (0.52) | KMT2ALMNASMN1; SMN2IDO1MLKL | |
| SCHEMBL6946091 | 0.73 | TDP1 (0.56) | KMT2ALMNASMN1; SMN2BCHEALDH1A1 | |
| SCHEMBL30689200 | 0.73 | TDP1 (0.56) | KMT2ALMNASMN1; SMN2BCHEALDH1A1 | |
| SCHEMBL21798473 | 0.73 | MTOR (0.53) | — | |
| SCHEMBL30034373 | 0.73 | MTOR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |