Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8329501 | 1.00 | KMT2A (0.57) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL13752131 | 0.96 | KMT2A (0.61) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL13495538 | 0.96 | KMT2A (0.61) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL15850937 | 0.96 | KMT2A (0.61) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL34473337 | 0.86 | KMT2A (0.57) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL4080893 | 0.83 | KMT2A (0.59) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL5626616 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL6947425 | 0.83 | KMT2A (0.59) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL13752129 | 0.83 | KMT2A (0.59) | KMT2AMAPK1GRM5P2RX3ALDH1A1 | |
| SCHEMBL6947422 | 0.83 | KMT2A (0.59) | KMT2AMAPK1GRM5P2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559774-B1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0909759-A2 | Individual stereoisomers of 7-(3-aminoalkyl)-1-pyrrolidinyl)-quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5633264-A | Individual stereoisomers of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-Quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5563155-A | QUINOLONE ANTIBIOTICS WITH INCREASED EFFICACY, REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5461165-A | Individual stereoisomers of intermediates of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5344940-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5258528-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009596-A1 | INDIVIDUAL STEREOISOMERS OF 7-[3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |