Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326039 | 0.92 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL8327835 | 0.91 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL8326558 | 0.90 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL8327899 | 0.89 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL8329147 | 0.89 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL8327362 | 0.88 | EDNRA (0.58) | EDNRAEDNRB | |
| SCHEMBL8328969 | 0.88 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL8326887 | 0.84 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL8327017 | 0.83 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL8323019 | 0.82 | EDNRA (0.54) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | claimed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |