Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328184 | 0.93 | EDNRB (0.69) | EDNRBEDNRA | |
| SCHEMBL8323034 | 0.89 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL7696041 | 0.85 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7696038 | 0.85 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL6785547 | 0.80 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7699764 | 0.79 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL7699763 | 0.79 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL7851485 | 0.78 | EDNRB (0.79) | EDNRBEDNRA | |
| SCHEMBL8327602 | 0.78 | EDNRA (0.83) | EDNRBEDNRA | |
| SCHEMBL7696657 | 0.78 | EDNRB (0.62) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | claimed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |