Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411544 | 0.93 | OPRL1 (0.42) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL18458718 | 0.93 | OPRL1 (0.42) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL10043332 | 0.89 | OPRL1 (0.39) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL19500489 | 0.87 | OPRL1 (0.39) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL18458714 | 0.87 | ESR2 (0.40) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL19159768 | 0.87 | OPRL1 (0.39) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL10043153 | 0.87 | OPRL1 (0.41) | OPRL1KMOACMSD | |
| SCHEMBL10043143 | 0.85 | OPRL1 (0.39) | OPRL1KMOACMSDBACE1HDAC4 | |
| SCHEMBL18558911 | 0.84 | ESR2 (0.40) | OPRL1KMOACMSDBACE1CYP3A4 | |
| SCHEMBL18900740 | 0.84 | OPRL1 (0.39) | OPRL1KMOACMSDBACE1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |