SCHEMBL832904

SCHEMBL832904

O=[C]C(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2383252 0.71
SCHEMBL11648251 0.69
SCHEMBL834665 0.69
SCHEMBL8406569 0.69
SCHEMBL834417 0.67
SCHEMBL1032378 0.67
SCHEMBL5402282 0.67
SCHEMBL8406567 0.67
SCHEMBL1030414 0.67
SCHEMBL13719051 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024131265-A1 COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF 中国科学院合肥物质科学研究院 2024-06-27 WO claimed
CN-118239953-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2024-06-25 CN claimed
WO-2024094170-A1 INHIBITOR OF UBIQUITIN-SPECIFIC PROTEASE 1 AND USE THEREOF 深圳晶泰科技有限公司 2024-05-10 WO claimed
US-20150080381-A1 METHODS OF TREATING ALOPECIA AND ACNE IRONWOOD PHARMACEUTICALS, INC. 2015-03-19 US claimed
US-8674115-B2 CRTH2 modulators IRONWOOD PHARMACEUTICALS, INC. (US) 2014-03-18 US claimed
WO-2013155422-A1 METHODS OF TREATING ALOPECIA AND ACNE IRONWOOD PHARMACEUTICALS, INC. (US) 2013-10-17 WO claimed
EP-2516416-A1 CRTH2 MODULATORS Ironwood Pharmaceuticals, Inc. (US) 2012-10-31 EP claimed
WO-2011079007-A1 CRTH2 MODULATORS IRONWOOD PHARMACEUTICALS, INC. (US) 2011-06-30 WO claimed
US-20110150834-A1 CRTH2 MODULATORS WELLS FARGO BANK, NATIONAL ASSOCIATION 2011-06-23 US claimed
US-5466684-A 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1995-11-14 US claimed
US-5328902-A Antibiotics AMERICAN CYANAMID CO. (US) 1994-07-12 US claimed
EP-0326054-B1 PROCESS FOR PURIFICATION OF 2,2,3,3-TETRAFLUOROOXETANE DAIKIN INDUSTRIES, LIMITED (JP) 1992-04-15 EP claimed
EP-0258911-B1 PROCESS FOR PREPARING 2,2,3-TRIFLUOROPROPIONYL FLUORIDE DAIKIN INDUSTRIES, LIMITED (JP) 1990-10-31 EP claimed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP claimed
WO-2024131265-A1 COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF 中国科学院合肥物质科学研究院 2024-06-27 WO disclosed
CN-118239953-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2024-06-25 CN disclosed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
US-4011341-A HERBICIDES ELI LILLY AND COMPANY (US) 1977-03-08 US disclosed
US-3989840-A Control of animal parasites with ring-substituted N-(2,2-difluoroalkanoyl)-O-phenylenediamines ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed
US-3962263-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed