Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090571 | 0.84 | CSNK1E (0.49) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| SCHEMBL28709961 | 0.84 | CSNK1E (0.49) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| SCHEMBL1091524 | 0.84 | CSNK1E (0.49) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| SCHEMBL13822592 | 0.82 | DPP4 (0.59) | DPP4KDM4ELMNAHTR2AF2 | |
| Hydrochloric Acid SCHEMBL4664397 | 0.82 | CSNK1E (0.47) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL11264234 | 0.82 | CSNK1E (0.47) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL4665738 | 0.82 | CSNK1E (0.47) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL1485805 | 0.82 | CSNK1E (0.47) | DPP4HTR2ACSNK1ESIGMAR1OPRM1 | |
| SCHEMBL27692950 | 0.82 | DPP4 (0.45) | DPP4HTR2AAOC3CSNK1EHRH1 | |
| SCHEMBL27692856 | 0.81 | CSNK1E (0.46) | DPP4HTR2AAOC3CSNK1ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038182-A9 | HYPOLIPIDEMIC BICYCLIC DERIVATIVES | GLAXO GROUP LTD (GB) | 1999-04-15 | — | — | WO | disclosed |
| WO-1998038182-A1 | HYPOLIPIDEMIC BICYCLIC DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |